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  • Title: Variability of bacterial vaginosis over 6- to 12-month intervals.
    Author: Ness RB, Kip KE, Soper DE, Stamm CA, Rice P, Richter HE.
    Journal: Sex Transm Dis; 2006 Jun; 33(6):381-5. PubMed ID: 16543864.
    Abstract:
    OBJECTIVES: To examine variability in bacterial vaginosis (BV) over 6- to 12-month intervals. STUDY DESIGN: One thousand one hundred ninety-three women were followed for a median of 3 years with serial vaginal swab Gram stains for BV. Discrete time hazard models were fit to identify independent risk factors for BV. RESULTS: Women with BV at study entry were categorized as having normal flora at the next visit 20% of the time, and women with normal flora at study entry were categorized as having BV at the next visit 20% of the time. Among women with initially normal flora, factors associated with BV were black race, lower education, a history of BV, a history of chlamydial/gonococcal cervicitis, and lack of monogamy. CONCLUSION: About one fifth of women with normal flora develop BV over a given 6- to 12-month interval, and the modifiable risk factors of cervicitis and lack of monogamy contribute to the development of BV.
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