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  • Title: A cytochemical study of some enzyme activities in biliverdin-treated cell cultures.
    Author: Paradisi F, Graziano L, de Ritis F.
    Journal: Pathol Biol (Paris); 1975 Feb; 23(2):101-5. PubMed ID: 165446.
    Abstract:
    The authors studied the modifications of the activities of some enzymes in cell cultures submitted to the action of biliverdin. This biliary pigment rapidly induces a remarkable increase in alkaline phosphatase and ATP-ase activities and subsequently, an activation of acid phosphatase and beta-glucuronidase. On the contrary, 5'-nucleotidase and glucose-6-phosphatase activities remain unchanged. These results are discussed and compared with those obtained in our and other laboratories by using unconjugated bilirubin on different biological substrates.
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