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  • Title: Identification of a diuretic hormone of Locusta migratoria.
    Author: Lehmberg E, Ota RB, Furuya K, King DS, Applebaum SW, Ferenz HJ, Schooley DA.
    Journal: Biochem Biophys Res Commun; 1991 Sep 16; 179(2):1036-41. PubMed ID: 1654896.
    Abstract:
    We have isolated a peptide from brains and corpora cardiaca of Locusta migratoria which is immunologically related to the diuretic hormone of Manduca sexta. We determined its structure as a 46 amino acid linear peptide with 43-50% identity to the M. sexta hormone. Moreover, we showed that the new peptide functions as a diuretic hormone in L. migratoria, stimulating urine production by Malpighian tubules and elevating levels of cAMP in tubules.
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