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  • Title: The Treponema denticola surface protease dentilisin degrades interleukin-1 beta (IL-1 beta), IL-6, and tumor necrosis factor alpha.
    Author: Miyamoto M, Ishihara K, Okuda K.
    Journal: Infect Immun; 2006 Apr; 74(4):2462-7. PubMed ID: 16552080.
    Abstract:
    Dentilisin is a major surface protease and virulence factor of the bacterium Treponema denticola. In this study, we found that T. denticola reduced inflammatory cytokines, including interleukin-1beta (IL-1beta), IL-6, and tumor necrosis factor alpha, in peripheral blood mononuclear cells through degradation by dentilisin.
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