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  • Title: The change of the split renal function before and after a nephrectomy using Tc-mercaptoacetyltriglycine (MAG3).
    Author: Harano M, Tokuda N, Ichikura H, Nakamura M, Eto M, Tatsugami K, Naito S.
    Journal: Fukuoka Igaku Zasshi; 2005 Dec; 96(12):391-8. PubMed ID: 16562500.
    Abstract:
    OBJECTIVE: We examined the change in the renal function in the normal side kidney before and after a nephrectomy, by means of a newly developed diuretic renography technique utilizing Tc 99m-mercaptoacetyltriglycine (MAG3). MATERIALS AND METHODS: Forty patients who underwent a nephrectomy were evaluated using MAG3 diuretic renography. We measured the effective renal plasma flow (ERPF) and Tmax time before and after a nephrectomy. The effects of the patient age and the preoperative ERPF of ill side kidney on the post operative ERPF were then assessed statistically. RESULTS: The ERPF increased by an average of 44.8 ml/min at 2 weeks after a nephrectomy, but it decreased by an average of 24.3 ml/min at 3 months after a nephrectomy. The Tmax time decreased by an average of 0.58 min at 2 weeks, but thereafter increased by an average of 0.58 min at 3 months after a nephrectomy. The correlation coefficient between the rate of increase in the ERPF and the patient age was 0.197. CONCLUSIONS: The rise of renal function in terms of ERPF and the Tmax time was observed at 2 weeks post-nephrectomy. However, this effect disappeared at 3 months post-nephrectomy. These data demonstrated that the rise in the renal function of the normal-side kidney in such patients was only temporary.
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