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  • Title: Remitting seronegative symmetrical synovitis pitting oedema after BCG instillation.
    Author: El Mahou S, Popa L, Constantin A, Cantagrel A, Aberrane A, Jamard B, Mazieres B, Laroche M.
    Journal: Clin Rheumatol; 2006 Jul; 25(4):566-7. PubMed ID: 16565898.
    Abstract:
    Remitting seronegative symmetrical synovitis pitting oedema (RS3PE) is a distinct form of seronegative rheumatoid arthritis like polyarthritis. It is characterized by late onset symmetrical joint involvement and pitting oedema of hands and feet (JAMA 254(19):2763-2767, [1]). Polyarthritis secondary to intravesical Bacillus Calmette Guerin (BCG) therapy has been reported (Clin Rheumatol 21:536-537, [2]). To our knowledge, about 0.5% of patients receiving BCG instillation presented polyarthritis, but only one case of RS3PE has been reported (J Rheumatol 28:1699-1701, [3]). We described the second case of RS3PE following intravesical BCG instillation of bladder carcinoma.
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