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Title: Differences in ion release after ceramic-on-ceramic and metal-on-metal total hip replacement. Medium-term follow-up. Author: Savarino L, Greco M, Cenni E, Cavasinni L, Rotini R, Baldini N, Giunti A. Journal: J Bone Joint Surg Br; 2006 Apr; 88(4):472-6. PubMed ID: 16567781. Abstract: Modern metal-on-metal bearings produce less wear debris and osteolysis, but have the potential adverse effect of release of ions. Improved ceramic-on-ceramic bearings have the lowest wear of all, but the corrosion process has not been analysed. Our aim was to measure the serum ion release (ng/ml) in 23 patients having stable hip prostheses with a ceramic-on-ceramic coupling (group A) and to compare it with the release in 42 patients with a metal-on-metal bearing (group B) in the medium term. Reference values were obtained from a population of 47 healthy subjects (group C). The concentrations of chromium, cobalt, aluminium and titanium were measured. There was a significant increase of cobalt, chromium and aluminium levels (p < 0.05) in group B compared with groups A and C. Group A did not differ significantly from the control group. Despite the apparent advantage of a metal-on-metal coupling, especially in younger patients with a long life expectancy, a major concern arises regarding the extent and duration of ion exposure. For this reason, the low corrosion level in a ceramic-on-ceramic coupling could be advantageous.[Abstract] [Full Text] [Related] [New Search]