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  • Title: Precursor B lymphoblastic leukemia 32 months after local therapy for a primary extramedullary myeloid cell tumor.
    Author: Szinnai G, Cogliatti SB, Avoledo P, Dirnhofer S, Schmid U, Kühne T.
    Journal: Pediatr Blood Cancer; 2007 Dec; 49(7):1039-46. PubMed ID: 16572408.
    Abstract:
    A primary extramedullary myeloid cell tumor (pEMT) of an inguinal lymph node was completely excised without subsequent anti-tumor therapy in a 6-year-old child. Clinical observation and monitoring of blood and bone marrow (BM) did not reveal any pathologic results before 32 months, when a precursor B lymphoblastic leukemia was diagnosed. Identical T-cell receptor gamma rearrangement in nodal pEMT and in precursor B lymphoblastic leukemia in BM indicates a clonal relationship of these two tumors.
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