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  • Title: Primary cutaneous nodular amyloidosis in a patient with Sjögren's syndrome.
    Author: Srivastava M.
    Journal: J Drugs Dermatol; 2006 Mar; 5(3):279-80. PubMed ID: 16573263.
    Abstract:
    A 71-year-old woman with a history of Sjögren's syndrome presented for evaluation of a waxy nodule present on the scalp for 6 months. Histopathologic examination revealed deposition of homogenous eosinophilic material throughout the reticular dermis consistent with amyloidosis. Primary cutaneous nodular amyloidosis is a rare phenomenon characterized by the deposition of immunoglobin light chains by a clonal plasma cell population. Patients need to be monitored for progression to systemic amyloidosis or plasma cell dyscrasias.
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