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  • Title: An intact peripheral nerve preparation for monitoring the activity of single, periosteal afferent nerve fibres.
    Author: Mahns DA, Ivanusic JJ, Sahai V, Rowe MJ.
    Journal: J Neurosci Methods; 2006 Sep 30; 156(1-2):140-4. PubMed ID: 16574241.
    Abstract:
    A preparation is described in which it is possible to selectively activate and monitor the activity of the individual periosteal afferent nerve fibres arising from the humerus bone of the cat. The nerve is a fine branch of the median nerve that accompanies the small artery and vein that enter the nutrient foramen of the humerus. By freeing this fine nerve from nearby tissue over a length of approximately 1-2 cm and placing it over a silver hook recording electrode, it becomes possible to identify and monitor electrophysiologically, the impulse activity of individual periosteal afferent fibres activated by focal mechanical stimulation of the periosteum. With this preparation it will be possible to examine the central actions and security of transmission at central synaptic targets for single, small-diameter afferent fibres arising from bone.
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