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  • Title: The bacteriologic yield in children with intrathoracic tuberculosis.
    Author: Marais BJ, Hesseling AC, Gie RP, Schaaf HS, Enarson DA, Beyers N.
    Journal: Clin Infect Dis; 2006 Apr 15; 42(8):e69-71. PubMed ID: 16575719.
    Abstract:
    This report documents the bacteriologic yield in children who received treatment for intrathoracic tuberculosis in an area where it is highly endemic. A total of 307 children were included in the study, and bacteriologic confirmation was achieved in 122 (62.2%) of 196 children from whom specimens were collected. The lowest bacteriologic yield was recorded for the 69 children with uncomplicated lymph node disease (24 [34.8%] had bacteriologic confirmation). The high overall bacteriologic yield indicates the need to reassess the value of bacteriology-based approaches to diagnosis of intrathoracic tuberculosis in children, particularly in areas of endemicity where they frequently present with advanced disease.
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