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Pubmed for Handhelds

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  • Title: Peroxisome proliferator-activated receptors and acute lung injury.
    Author: Cuzzocrea S.
    Journal: Curr Opin Pharmacol; 2006 Jun; 6(3):263-70. PubMed ID: 16580256.
    Abstract:
    Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily of ligand-activated transcription factors that are related to retinoid, steroid and thyroid hormone receptors. The PPAR subfamily comprises three members: PPAR-alpha, PPAR-beta and PPAR-gamma. PPARs have recently been implicated as regulators of cellular proliferation and inflammatory responses. Furthermore, it has been demonstrated that PPAR-gamma and PPAR-alpha reduce lung injury associated with inflammation and shock.
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