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  • Title: [Treatment of infantile spasms].
    Author: Hansen LK, Rasmussen NH.
    Journal: Ugeskr Laeger; 2006 Apr 03; 168(14):1424-8. PubMed ID: 16584670.
    Abstract:
    Infantile spasms (IS) are characterised by neurodevelopmental regression, a unique type of seizures and a hypsarrhythmic EEG pattern. Studies recommend the medical treatment of IS as a positive short-term outcome with respect to the spasms and in the resolution of the hypsarrhythmia. However, the data are insufficient to recommend medical treatment with respect to improving the long-term outcome. The adrenocorticotropic hormone and prednisolone are recommended for treatment of IS, although side effects are common. Vigabatrin is also recommended; IS caused by tuberous sclerosis seems to respond especially well.
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