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  • Title: Management of acute renal failure in the newborn.
    Author: Moghal NE, Embleton ND.
    Journal: Semin Fetal Neonatal Med; 2006 Jun; 11(3):207-13. PubMed ID: 16584932.
    Abstract:
    Acute renal failure is common in the neonatal period. It is usually manifest by abnormal biochemistry and decreased urine output (<1 ml/kg/h), but non-oliguric renal failure is also common. A detailed understanding of the common pathophysiological mechanisms is rarely needed but an understanding of the common aetiologies (pre-renal, renal and post-renal) will enable the clinician to approach the problem in a logical manner. A standard approach to fluid and electrolyte management is described, along with a practical approach to the investigation and management of renal failure. A working understanding of the principles of peritoneal dialysis is important and a brief overview of the role of haemodialysis in neonatal renal failure is provided.
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