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  • Title: Use of the TandemHeart percutaneous ventricular assist device to support patients undergoing high-risk percutaneous coronary intervention.
    Author: Kar B, Forrester M, Gemmato C, Civitello A, Loyalka P, Myers T, Reynolds D.
    Journal: J Invasive Cardiol; 2006 Mar; 18(3):93-6. PubMed ID: 16598104.
    Abstract:
    OBJECTIVES: We describe our experience in using the TandemHeart percutaneous ventricular assist device (pVAD) during high-risk percutaneous coronary intervention (PCI). BACKGROUND: Coronary artery bypass grafting (CABG) is the preferred treatment for disease in an unprotected left main coronary artery or left main equivalent. However, severe comorbidities may preclude surgery in some patients. In these cases, PCI is also often a high-risk procedure. The pVAD is designed to provide circulatory support during high-risk PCI. METHODS AND RESULTS: We used the pVAD for hemodynamic support during PCI in 5 consecutive patients who were ineligible for CABG because of severe comorbidities. In all 5 cases, the device was inserted and support initiated without complications. Percutaneous revascularization was successfully performed with pVAD support (approximately 3 L per minute). Four patients were supported for an average of 107 minutes, the pVAD being withdrawn shortly after PCI; all 4 patients recovered uneventfully. The fifth patient required support for 48 more hours after the procedure because of poor ventricular function. He died of heart failure and severe mitral regurgitation 10 days after pVAD withdrawal. CONCLUSIONS: The pVAD may provide sufficient circulatory support for hemodynamic protection during high-risk PCI, thus improving morbidity and mortality and broadening the therapeutic options for high-risk patients. Further investigation of this device is warranted.
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