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  • Title: Panagrellus redivivus: failure to find evidence for the occurrence and biosynthesis of sialic acids.
    Author: Reuter G, Aumann J, Wyss U, Jansson HB, Schauer R.
    Journal: Exp Parasitol; 1991 Nov; 73(4):389-95. PubMed ID: 1659991.
    Abstract:
    The occurrence of sialic acids in the free-living nematode Panagrellus redivivus was studied by periodate oxidation/[3H]sodium borohydride reduction of about 10(7) nematodes. In parallel, the capability of sialic acid biosynthesis was examined by metabolic labeling of the same number of nematodes with N-[3H]acetylmannosamine. In both experiments, radioactivity was incorporated into the nematodes. Mild acid hydrolysis, however, did not release radioactively labeled sialic acids or derivatives as tested by radio thin-layer chromatography, suggesting that P. redivivus does not contain or synthesize sialic acids.
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