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  • Title: [Cold-induced changes in blood lipoproteins in normotensive and hypertensive rats].
    Author: Kozyreva TV, Lomakina SV, Tuzikov FV, Tuzikova NA.
    Journal: Patol Fiziol Eksp Ter; 2006; (1):20-2. PubMed ID: 16607890.
    Abstract:
    It is shown that in thermoneutral conditions ISIAH (Inherited Stress-Induced Arterial Hypertension) hypertensive rats had a lower level of high-density lipoproteins (HDLP) in plasma and a higher atherogenic coefficient compared to normotensive Wistar rats. After cooling there were different changes in fractional composition of plasma lipoproteins both in normo- and hypertensive rats. These changes depended on the cooling rate and were more pronounced after slow cooling. Slow cooling resulted in a more significant increase of plasma HDLP and in a greater decrease in LDLP and atherogenic coefficient in hypertensive rats compared to normotensive ones.
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