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  • Title: Anomalies of the fingers and toes associated with Klippel-Trenaunay syndrome.
    Author: McGrory BJ, Amadio PC, Dobyns JH, Stickler GB, Unni KK.
    Journal: J Bone Joint Surg Am; 1991 Dec; 73(10):1537-46. PubMed ID: 1660897.
    Abstract:
    Klippel-Trenaunay syndrome is a rare congenital malformation characterized by a large angiomatous nevus; hypertrophy of soft tissue or overgrowth of bone, or both; and venous varicosities. The cases of 108 patients who had a diagnosis of this syndrome between 1956 and 1990 were reviewed. One hundred and twenty-six anomalies were found in twenty-nine patients, each of whom had one to thirteen malformations of the fingers or toes, or both. The ratio of female patients to male patients was approximately two to one. Twenty-six patients had macrodactyly affecting one to six digits; nine, syndactyly involving two or more digits; five, metatarsus primus varus; two, clinodacytly; two, polydactyly; one, camptodactyly; and one, a congenital trigger finger. Thirty-three of the 126 anomalies were in extremities that had no nevi, varicose veins, or generalized hypertrophy.
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