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  • Title: Transcatheter arterial embolization in patients with bleeding duodenal ulcer: an alternative to surgery.
    Author: Holme JB, Nielsen DT, Funch-Jensen P, Mortensen FV.
    Journal: Acta Radiol; 2006 Apr; 47(3):244-7. PubMed ID: 16613304.
    Abstract:
    PURPOSE: To evaluate the efficacy and safety of transcatheter arterial embolization (TAE) in patients with bleeding/rebleeding duodenal ulcers. MATERIAL AND METHODS: Over a 6-year-period, 40 consecutive patients with bleeding/ rebleeding after endoscopic therapy and/or surgery for duodenal ulcer were included in the study. Superselective angiographic catheterization and coil embolization were performed by the same interventional radiologist. RESULTS: Lasting hemostasis was achieved in 26 of 40 patients (65%). Transfusion requirement was reduced from median 14 (range 3-35) units of blood before TAE to 2 (range 0-53) units after TAE. Ten patients died, five because of continuous bleeding. No adverse effects as a result of TAE were seen. CONCLUSION: TAE is an effective and safe treatment in a significant proportion of patients with bleeding duodenal/rebleeding ulcers after therapeutic endoscopy and/or surgery.
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