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Title: Bent out of shape: RNA unwinding by the DEAD-box helicase Vasa. Author: Linder P, Lasko P. Journal: Cell; 2006 Apr 21; 125(2):219-21. PubMed ID: 16630807. Abstract: RNA helicases of the DEAD-box family are involved in essentially all RNA-dependent cellular processes. In this issue of Cell, Sengoku et al. (2006) solve the structure of the DEAD-box protein Vasa in the presence of RNA and a nonhydrolyzable ATP analog and provide important insights into how this family of helicases unwinds RNA.[Abstract] [Full Text] [Related] [New Search]