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  • Title: [Simultaneous liver-pancreas-duodenum transplantation: one case report and review of the literature].
    Author: Xu J, Yu LX, Deng WF, Fu SJ, Du CF, Wang YB, Liu XY, Miao Y, Li CJ, Ye JS.
    Journal: Zhonghua Wai Ke Za Zhi; 2006 Feb 01; 44(3):157-60. PubMed ID: 16635342.
    Abstract:
    OBJECTIVE: To investigate the effect of treatment on end-stage liver disease and type-I diabetes mellitus with simultaneous liver-pancreas-duodenum transplantation. METHOD: In September 2003, one patient with chronic hepatitis B, liver cirrhosis, hepatic cellular cancer, and insulin-dependent diabetes received simultaneous orthotopic liver and heterotopic pancreas-duodenum transplantation. Liver and pancreas graft function was monitored after transplantation. RESULTS: The function of pancreas allograft was recovered immediately and the patient became insulin-independence postoperatively. The liver allograft was experienced an acute rejection episode and reversed by intravenous bolus methylprednisolone. The recipient was currently liver disease-free and insulin-free more than 21 months. CONCLUSIONS: The simultaneous liver-pancreas-duodenum transplantation is an effective method in the treatment of end-stage liver disease and type-I diabetes mellitus.
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