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  • Title: Lignans from Saussurea conica and their NO production suppressing activity.
    Author: Fan CQ, Zhu XZ, Zhan ZJ, Ji XQ, Li H, Yue JM.
    Journal: Planta Med; 2006 Jun; 72(7):590-5. PubMed ID: 16636966.
    Abstract:
    Three new lignan derivatives, conicaols A and B and conicaoside, together with seven known compounds were identified from Saussurea conica. Their structures were elucidated by spectral methods including 1D and 2D NMR techniques. Six 2,3-dibenzylbutyrolactone-type lignans were biologically evaluated, and two of them, arctigenin and matairesinol, showed potent activity to suppress NO production in vitro in LPS-activated macrophages of SD rat.
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