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  • Title: The mismatch problem for GABAergic amacrine cells in goldfish retina: resolution and other issues.
    Author: Yazulla S.
    Journal: Neurochem Res; 1991 Mar; 16(3):327-39. PubMed ID: 1664059.
    Abstract:
    GABAergic neurons in the vertebrate retina have received intensive study. Yet there are several notable examples of a "mismatch" among the cytochemical markers used to identify GABAergic neurons. The mismatch between [3H]GABA uptake autoradiography and all other indicators of GABAergic neurons as they pertain to amacrine cells in goldfish retina is examined in this overview. The discrepancies can be accounted for largely by barriers to diffusion presented by significant GABA uptake sinks at the inner and outer margins of the retina and by the differential subcellular distribution of the various markers for GABAergic neurons. Also, conditions producing a redistribution of [3H]-GABA and endogenous GABA stores within the retina are described and discussed.
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