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  • Title: A large ulcer and cutaneous small-vessel vasculitis associated with syphilis infection.
    Author: Chao YC, Chen CH, Chen YK, Chou CT.
    Journal: Scand J Rheumatol; 2006; 35(2):147-51. PubMed ID: 16641051.
    Abstract:
    Cutaneous vasculitis (CV) is a condition with cutaneous manifestations and possible systemic involvement. The causative factors or associated diseases are usually drugs, infection, collagen vascular disease, or malignancy. Syphilis as a cause of cutaneous vasculitis is rare. We report the case of a large cutaneous ulcer and small-vessel vasculitis associated with syphilis infection. We suggest that in apparently idiopathic CV or a chronic ulcer refractory to treatment, screening should be performed to detect any underlying infection such as syphilis. It is important to have a rapid and accurate diagnosis because the lesions are very contagious, but may be rapidly and completely cured by early administration of antibiotic treatment.
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