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  • Title: Caryophyllene sesquiterpenoids from a fungicolous isolate of Pestalotiopsis disseminata.
    Author: Deyrup ST, Swenson DC, Gloer JB, Wicklow DT.
    Journal: J Nat Prod; 2006 Apr; 69(4):608-11. PubMed ID: 16643036.
    Abstract:
    Three new caryophyllene-type sesquiterpene alcohols, 6-hydroxypunctaporonin E (1), 6-hydroxypunctaporonin B (2), and 6-hydroxypunctaporonin A (3), have been isolated from cultures of the fungicolous fungus Pestalotiopsis disseminata. The structures of 1-3 were determined mainly by analysis of 1D and 2D NMR data. The structure and absolute configuration of 6-hydroxypunctaporonin E (1) was confirmed through X-ray crystallographic analysis of its mono-bromobenzoate derivative. Compounds 1 and 2 showed activity against Gram-positive bacteria.
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