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  • Title: Bisabolane sesquiterpenes from the roots of Ligularia cymbulifera.
    Author: Liu CM, Fei DQ, Wu QH, Gao K.
    Journal: J Nat Prod; 2006 Apr; 69(4):695-9. PubMed ID: 16643057.
    Abstract:
    Eight new highly oxygenated bisabolane sesquiterpenes (1-8), of which one contains a chlorine atom, were obtained in a phytochemical investigation of the roots of Ligularia cymbulifera, and their structures were elucidated by interpretation of spectroscopic data. Their relative configurations were clarified by a detailed analysis of (1)H NMR coupling constants and by NOE experiments. Compounds 1-8 were evaluated for antimicrobial activity against three bacterial cultures and a yeast culture.
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