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  • Title: Benefits of combining aripiprazole to clozapine: three case reports.
    Author: Rocha FL, Hara C.
    Journal: Prog Neuropsychopharmacol Biol Psychiatry; 2006 Aug 30; 30(6):1167-9. PubMed ID: 16647796.
    Abstract:
    OBJECTIVE: A substantial number of patients treated with clozapine shows insufficient response. The author presents the results of adding aripiprazole in patients resistant to clozapine. METHOD: Three cases of individuals with psychotic symptoms despite clozapine use and with significant side effects that were treated via this combination are presented. Response was evaluated by clinical assessment. RESULTS: Good clinical results were obtained in all three patients, with improvement of psychotic symptoms and of some of the side effects of clozapine. CONCLUSION: The findings from this case series suggest that adjunctive therapy with aripiprazole can be of benefit for treating clozapine resistant schizophrenic patients.
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