These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: In-vitro activity of temafloxacin for gram-positive pathogens.
    Author: Bille J, Glauser MP.
    Journal: J Antimicrob Chemother; 1991 Dec; 28 Suppl C():9-14. PubMed ID: 1664835.
    Abstract:
    The antimicrobial activity of temafloxacin against aerobic Gram-positive cocci was compared to that of ciprofloxacin, ofloxacin, fleroxacin and pefloxacin using the broth microdilution technique. Temafloxacin was more active than the other four fluoroquinolones, particularly for viridans streptococci and Streptococcus pneumoniae. The MIC90 of temafloxacin was at least four-fold lower than that of ciprofloxacin and ofloxacin for viridans streptococci and penicillin-susceptible pneumococci. The MIC50s and MIC90s of temafloxacin were equal to or lower than those of the other fluoroquinolones for methicillin-susceptible Staphylococcus aureus (MSSA), methicillin-resistant S. aureus (MRSA), and methicillin-susceptible and methicillin-resistant coagulase-negative staphylococci. Temafloxacin was more active against all the other Gram-positive aerobes (except Enterococcus faecalis) tested than the other fluoroquinolones.
    [Abstract] [Full Text] [Related] [New Search]