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  • Title: Ginsenoside Rg8, a new dammarane-type triterpenoid saponin from roots of Panax quinquefolium.
    Author: Dou D, Li W, Guo N, Fu R, Pei Y, Koike K, Nikaido T.
    Journal: Chem Pharm Bull (Tokyo); 2006 May; 54(5):751-3. PubMed ID: 16651785.
    Abstract:
    A new dammarane-type triterpenoid saponin, ginsenoside Rg(8) (1), was isolated from the roots of Panax quinquefolium, along with five known saponins, (20E)-ginsenoside F(4) (2), ginsenosides Rh(1) (3), Rg(2) (4), F(1) (5), and (20R)-ginsenoside Rh(1) (6). The structure of ginsenoside Rg(8) (1) was determined to be (3beta,6alpha,12beta,20E)-24,25-epoxy-3,12,23-trihydroxydammar-20(22)-en-6-O-alpha-L-rhamnopyranosyl(1-->2)-beta-D-glucopyranoside by various spectroscopic analyses. Among the known saponins, (20E)-ginsenoside F(4) (2) and ginsenoside F(1) (5) were first reported from the title plant.
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