These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [The effect of N-bromoacetamide on the components of sodium channel inactivation in the membrane of Ranvier's node].
    Author: Lonskiĭ AV, Krutetskaia ZI, Roshchina NG, P'iankova SV.
    Journal: Fiziol Zh SSSR Im I M Sechenova; 1991 May; 77(5):53-60. PubMed ID: 1666379.
    Abstract:
    In voltage clamp experiments on the frog Ranvier node, the specific protein reagent, N-bromacetamide, significantly decelerates the sodium inactivation kinetics and makes it incomplete. After treatment with N-bromacetamide, both fast and slow inactivation time constants are increased and the proportion of inactivation components is changed favouring the slowly inactivating one in the wide range of membrane potentials. The results are consistent with a single channel population following the 3-state model of inactivation.
    [Abstract] [Full Text] [Related] [New Search]