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  • Title: [Different action of alpha-methyl-DOPA on sleep and labyrinth learning in 2 inbred strains of mice].
    Author: Kitahama K, Valatx JL, Jouvet M.
    Journal: C R Acad Hebd Seances Acad Sci D; 1975 Jan 27; 280(4):471-4. PubMed ID: 166767.
    Abstract:
    In two inbred mice strains C 57 BR and C 57 BL/6 presenting the same type of sleep, but a different capacity of learning, Alpha-Methyl-Dopa (100 mg/kg) injected after every session, suppresses paradoxical sleep completely for 9 to 11 h. Maze-learning performance is retarded in C 57 BR mice, but facilitated in C 57 BL/6.
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