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  • Title: Basic fibroblast growth factor promotes nerve regeneration in a C- -ion-implanted silicon chamber.
    Author: Ikeguchi R, Kakinoki R, Matsumoto T, Yamakawa T, Nakayama K, Morimoto Y, Tsuji H, Ishikawa J, Nakamura T.
    Journal: Brain Res; 2006 May 23; 1090(1):51-7. PubMed ID: 16677621.
    Abstract:
    We reported previously that a silicone tube whose inner surface has been implanted with negatively charged carbon ions (C-) enables a nerve to regenerate across a 15-mm inter-stump gap. In this study, we investigated whether a C- -ion-implanted tube pretreated with basic fibroblast growth factor promotes peripheral nerve regeneration. The C- -ion-implanted tube significantly accelerated nerve regeneration, and this effect was enhanced by basic fibroblast growth factor.
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