These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: p53 protein and bcl-2 expression in glioblastomas. Pathological correlations in a comprehensive series.
    Author: Ardeleanu C, Ceauşu M, Butur G, Grămadă ZF, Dănăilă L, Hălălău F, Arsene D.
    Journal: Rom J Morphol Embryol; 2005; 46(4):275-8. PubMed ID: 16688362.
    Abstract:
    p53 and bcl-2 are two well-known antiapoptotic factors associated with gliomas, and mostly astrocytic tumors. In the present study we assessed, by immunohistochemistry, the expression of these two factors in a series of 50 glioblastomas. The correlations between their expression and several tumor-related factors (age, location, recurrence, proliferating potential) were investigated. Our results suggest that a valuable correlation between these factors cannot be found. This is in discrepancy with some literature data, which emphasize strong relations of p53 and bcl-2 in oncogenesis spreading or final prognosis. Further studies are needed, with unique, standard procedures for these evaluations.
    [Abstract] [Full Text] [Related] [New Search]