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  • Title: [Endobronchial stenosis in Wegener's granulomatosis].
    Author: Hervier B, Pagnoux C, Renaudin K, Masseau A, Pottier P, Planchon B, Guillevin L, Hamidou M.
    Journal: Rev Med Interne; 2006 Jun; 27(6):453-7. PubMed ID: 16697082.
    Abstract:
    INTRODUCTION: Endobronchial stenoses are rare in the course of Wegener's granulomatosis, and they occur even more rarely than subglottic stenoses. EXEGESIS: We report seven cases of endobronchial stenoses in the setting of Wegener granulomatosis. Neither the pulmonary symptoms nor the systemic manifestations of vasculitis were specific. However 6/7 patients presented a wheezing or an hemoptysis. Bronchial endoscopy has permitted the diagnosis in all cases. Local evolution was cicatricial and symptomatic stenosis in 3 cases (42,8%). CONCLUSION: Thus these lesions must be research in any case of pulmonary abnormality in the course of Wegener's granulomatosis, because they may lead to a pejorative prognosis. Moreover general and local treatment must be given early (at the inflammatory stage). After this stage, the local treatments are difficult and not efficient.
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