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  • Title: Crystal structure, spectroscopic, and biological study of the copper(II) complex with third-generation quinolone antibiotic sparfloxacin.
    Author: Efthimiadou EK, Sanakis Y, Raptopoulou CP, Karaliota A, Katsaros N, Psomas G.
    Journal: Bioorg Med Chem Lett; 2006 Jul 15; 16(14):3864-7. PubMed ID: 16697195.
    Abstract:
    The neutral mononuclear copper(II) complex with the quinolone antibacterial drug sparfloxacin has been prepared and characterized with IR, UV-vis, and EPR spectroscopies and X-ray crystallography. The interaction of the complex with calf-thymus DNA has also been investigated and the antimicrobial activity has been evaluated against three different microorganisms.
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