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  • Title: [Retinopathy in a patient with hepatitis C treated with pegylated interferon and ribavirin: case report].
    Author: Avila MP, Freitas AM, Isaac DL, Bastos AL, Pena RV.
    Journal: Arq Bras Oftalmol; 2006; 69(2):255-9. PubMed ID: 16699680.
    Abstract:
    Interferon is an immunomodulating cytokine used to treat patients with different diseases, such as hepatitis C chronic infection. Pegylated interferon is a new type of interferon, developed to increase the half-life of the drug. Many side effects have been related to its use, including ocular toxicity and retinopathy. The most reported ocular findings are cotton-wool spots and hemorrhages located at the posterior pole and surrounding optic nerve head. We describe one case of pegylated interferon-associated retinopathy with visual loss. The patient had visual acuity improvement four weeks after discontinuation of the medication and the ocular findings became much more subtle.
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