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  • Title: Bacillus Calmette-Guerin, Mycobacterium bovis, as an immunomodulator in atopic diseases.
    Author: Barlan I, Bahceciler NN, Akdis M, Akdis CA.
    Journal: Immunol Allergy Clin North Am; 2006 May; 26(2):365-77, ix. PubMed ID: 16701150.
    Abstract:
    Based on the hygiene hypothesis association between atopy and bacillus Calmette-Guerin (BCG), purified protein derivative skin test reaction, mycobacterial disease, and environmental mycobacteria are summarized. The role of mycobacterial species in the activation of the innate immune response through Toll-like receptors is mentioned. The implications and perspectives of BCG as a potential therapeutic adjuvant in atopic disease are discussed.
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