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  • Title: Well-differentiated chondrosarcoma of the humerus with prominent granular cell component: a hitherto unreported occurrence.
    Author: Cremonini A, Kuhn E, De Biase P, Franchi A.
    Journal: Int J Surg Pathol; 2006 Apr; 14(2):147-54. PubMed ID: 16703180.
    Abstract:
    We report the case of a well-differentiated chondrosarcoma of the proximal humerus in a 60-year-old man that featured a prominent component of granular cells, the granules being shown by electron microscopy to be lysosomal. Although secondary granular cell changes have been described in a large variety of tumor types, this is, to the best of our knowledge, the first documentation of this phenomenon in a skeletal chondrosarcoma.
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