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Title: Adjuvant aromatase inhibitor therapy for early breast cancer: A review of the most recent data. Author: Grana G. Journal: J Surg Oncol; 2006 Jun 01; 93(7):585-92. PubMed ID: 16705732. Abstract: Tamoxifen is the established adjuvant treatment for postmenopausal women with hormone-sensitive early breast cancer. However, the side-effects associated with tamoxifen therapy have prompted a search for safer and potentially more effective endocrine agents. Results from randomized trials of the third-generation aromatase inhibitors, anastrozole, letrozole and exemestane, demonstrating improved efficacy compared with tamoxifen and favorable tolerability profiles, are discussed in this review.[Abstract] [Full Text] [Related] [New Search]