These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Correlation between dynamic contrast-enhanced MRI and expression of microvascular density in the glioma].
    Author: Yin D, Wang XY, Yan XB, Liao WH.
    Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2005 Dec; 30(6):686-9. PubMed ID: 16708810.
    Abstract:
    OBJECTIVE: To explore the correlation between microvascular density (MVD) and dynamic contrast-enhanced MRI in the glioma. METHODS: We examined 35 patients with histologically verified glioma. Gadolinium-enhanced dynamic TurboFLASH imaging was performed preoperatively in all patients followed by conventional MRI. The steepest slope (SSmax) of curve and corresponding Tm1 in "first-pass" phase were obtained by analyzing time-signal curve. All specimens were immunostained with anti-human Factor VIII relative antigen monoclonal antibody postoperatively by streptavidin-peroxidase method to obtain the MVD. The correlation between SSmax, Tm1, and MVD was analyzed. RESULTS: SSmax was positively correlated with MVD (r = 0.640, P < 0.01). Tml was negatively correlated with MVD (r = -0.671, P < 0.01). CONCLUSION: The MVD correlates obviously with SSmax and Tml in the glioma. Analyzing the time-signal curve of dynamic contrast-enhanced MRI is helpful to predict the angiogenesis in the glioma.
    [Abstract] [Full Text] [Related] [New Search]