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  • Title: Non-infectious aortitis: an important cause of severe aortic regurgitation.
    Author: Chau EM, Wang E, Chiu CS, Chow WH.
    Journal: Asian Cardiovasc Thorac Ann; 2006 Jun; 14(3):177-82. PubMed ID: 16714691.
    Abstract:
    From 1995 to 2004, 13 patients with severe aortic regurgitation due to non-infectious aortitis underwent aortic valve surgery at our center. Twenty-eight operations (18 aortic valve replacements and 10 Bentall procedures including 1 aortic root replacement with a homograft) were performed due to a high incidence of prosthetic valve or valved conduit dehiscence (54%). Steroid therapy reduced the incidence of re-operation for anastomotic dehiscence within one year from 90% to 18%. Strategies to prevent dehiscence of the prosthetic aortic valve, which include institution of immunosuppression, replacement of the diseased aorta, and monitoring inflammatory indices, are discussed.
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