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  • Title: Neuromyelitis optica diagnosis in clinically isolated syndromes suggestive of multiple sclerosis.
    Author: Rubiera M, Río J, Tintoré M, Nos C, Rovira A, Téllez N, Montalban X.
    Journal: Neurology; 2006 May 23; 66(10):1568-70. PubMed ID: 16717222.
    Abstract:
    The authors assessed the extent of overlap between current diagnostic criteria of neuromyelitis optica (NMO) and multiple sclerosis (MS) by applying NMO criteria to a large cohort of 320 patients with clinically isolated syndromes (CIS). Twenty-three (7.2%) patients fulfilled NMO absolute criteria at some time and 1 (0.3%) also fulfilled one major supportive criterion. Therefore, even by systematically applying NMO criteria in patients with CIS, NMO diagnosis is reached infrequently.
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