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  • Title: [Application of four ELISA techniques (two for IgM and two for IgG) for serological diagnosis of an outbreak of Q fever].
    Author: Sanz JC, de los Ríos R, Martín F, Tébar MA, Jado I, Anda P.
    Journal: Enferm Infecc Microbiol Clin; 2006 Mar; 24(3):178-81. PubMed ID: 16722013.
    Abstract:
    OBJECTIVE: To evaluate four ELISAs (commercialized by Panbio and Serion) for IgM and IgG detection in an outbreak of Q fever. METHODS: Fifty-three serum samples corresponding to 29 persons were processed. An indirect immunofluorescence assay was used as the reference method. RESULTS: The sensitivity and specificity for IgM were 100% and 74% (Panbio), and 91% and 88% (Serion). IgG sensitivity was 72% (Panbio) and 89% (Serion). The specificity of both techniques for IgG was 97%. CONCLUSIONS: Both ELISAs seem to be good IgM screening methods for use during Q fever outbreaks.
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