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  • Title: Dopamine agonist therapy for Parkinson disease and pathological gambling.
    Author: Imamura A, Uitti RJ, Wszolek ZK.
    Journal: Parkinsonism Relat Disord; 2006 Dec; 12(8):506-8. PubMed ID: 16723269.
    Abstract:
    We report 6 patients with pathological gambling during pharmacologic treatment for Parkinson disease (PD). Four patients were treated with levodopa/carbidopa and dopamine agonist (DA), and 2 patients received DA monotherapy. We reviewed several published reports regarding pathological gambling and antiparkinsonian therapy and suggest that more advanced PD and antiparkinsonian combination therapy (e.g., levodopa/carbidopa and DA) increases the risk for development of pathological gambling behavior compared with monotherapy with either DA or levodopa/carbidopa.
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