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PUBMED FOR HANDHELDS

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  • Title: Chromatin in pluripotent embryonic stem cells and differentiation.
    Author: Meshorer E, Misteli T.
    Journal: Nat Rev Mol Cell Biol; 2006 Jul; 7(7):540-6. PubMed ID: 16723974.
    Abstract:
    Embryonic stem (ES) cells are unique in that they are pluripotent and have the ability to self-renew. The molecular mechanisms that underlie these two fundamental properties are largely unknown. We discuss how unique properties of chromatin in ES cells contribute to the maintenance of pluripotency and the determination of differentiation properties.
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