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  • Title: [Non-small cell lung cancer (NSCLC): the evolution of neo-adjuvant chemotherapy in the last 15 years].
    Author: Santo A, Genestreti G, Fiorio E, Terzi A, Lonardoni A, Calabrò F, Campaldini B, Colaluca P, Molino A, Cetto GL.
    Journal: Recenti Prog Med; 2006 Apr; 97(4):211-8. PubMed ID: 16729492.
    Abstract:
    Retrospective analysis of surgical data-base of NSCLC have showed that, except stage IA, the prognosis of locally advanced disease is very poor if treated with surgery and/or radiotherapy and it is probably due to distant micrometastasis present at the diagnosis. The aim of neo-adjuvant chemotherapy is to address early the distant micrometastasis and to allow, through a downstaging, surgical resection of tumor not suitable to surgery or partially respectable at diagnosis.
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