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  • Title: Monomelic parkinsonian tremor caused by contralateral substantia nigra stroke.
    Author: Gonzalez-Alegre P.
    Journal: Parkinsonism Relat Disord; 2007 Apr; 13(3):182-4. PubMed ID: 16731026.
    Abstract:
    Patients with Parkinson's disease have been frequently classified by their most prominent symptoms into tremor-predominant and akinetic/rigid variants. A few pathological studies have suggested that these different phenotypes represent topographical differences in nigral pathology. A patient is described in whom a medial substantia nigra stroke led to contralateral lower extremity parkinsonian tremor, providing a clinical-pathological correlation of this tremor, indicating a somatotopic organization of the substantia nigra and supporting the central generator hypothesis of parkinsonian tremor.
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