These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Parenteral lorazepam versus parenteral haloperidol for the control of psychotic disruptive behavior.
    Author: Salzman C, Solomon D, Miyawaki E, Glassman R, Rood L, Flowers E, Thayer S.
    Journal: J Clin Psychiatry; 1991 Apr; 52(4):177-80. PubMed ID: 1673123.
    Abstract:
    In a double-blind, prospective study, 2 mg of intramuscular lorazepam and 5 mg of intramuscular haloperidol were equally effective in controlling aggression, agitation, and assaultive behavior. Although lorazepam and haloperidol produced an equivalent mean decrease in aggression, significantly more subjects who received lorazepam had a greater decrease in aggression ratings than haloperidol recipients; this effect was independent of sedation. Lorazepam produced significantly fewer extrapyramidal symptoms. These data support the current clinical practice of using lorazepam (alone, or in combination with a neuroleptic) for control of acute aggressive and assaultive behavior.
    [Abstract] [Full Text] [Related] [New Search]