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  • Title: [Spermatocytic seminoma with rhabdomyosarcomatous contingent].
    Author: Chelly I, Mekni A, Gargouri MM, Bellil K, Zitouna M, Horchani A, Kchir N.
    Journal: Prog Urol; 2006 Apr; 16(2):218-20. PubMed ID: 16734251.
    Abstract:
    INTRODUCTION: Spermatocytic seminoma is a relatively rare testicular tumour, not associated with another germ-cell tumour component and characterized by a favourable prognosis. However, discovery of a sarcomatous contingent modifies the prognosis. MATERIAL AND METHOD: The authors report the case of a 50-year-old man with a history of right testicular swelling for 4 years, gradually increasing in size without vaginal effusion. Tumour markers were normal. Ultrasound demonstrated a very large semi-solid semi-cystic testicular mass with a long axis of 14 cm. Orchidectomy was performed. RESULT: Histological examination and immunohistochemistry of the orchidectomy specimen concluded on spermatocytic seminoma associated with a rhabdomyosarcomatous component. CONCLUSION: Only 12 cases of spermatocytic seminoma with sarcomatous component have been reported in the literature The presence of a sarcomatous component confers a very poor prognosis to spermatocytic seminoma.
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