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  • Title: Long-term zidovudine therapy in patients with AIDS and symptomatic and asymptomatic HIV infection.
    Author: Ebert S, Gockel K, Horowitz S, Weber P, Vogelman B, Graziano F.
    Journal: Wis Med J; 1991 Apr; 90(4):161-5. PubMed ID: 1675028.
    Abstract:
    Zidovudine is the only anti-retroviral drug approved by the FDA for treatment of HIV infection. We have examined the clinical and laboratory efficacy of this drug for 4 years in a cohort of HIV-infected patients from Wisconsin. Overall, we have found that individuals with AIDS will have at least 1 year of symptom reduction while on the drug. Those with asymptomatic HIV infection tolerate the drug and none have progressed to AIDS in the 4 years of study. Zidovudine is an important component in the treatment of HIV infection.
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